Delineation of an Isodicentric Y Chromosome in a Mosaic 45,X/46,X,idic(Y)(qter-p11.3:: p11.3-qter) Fetus by SRY Sequencing, G-banding, FISH, SKY and Study of Distribution in Different Tissues
Many factors such as genetic, developmental and hormonal are involved in mammalian sex determination.The relative importance and the mutual interactions among those factors are obscure.Study of cytogenetic mosaicism involving sex chromosomes may help to further unravel the mysterious process.We report a fetus with a mosaic bg tuley karyotype, 45,X/